Tools commonly used in the Animals-Laboratory Use industry for day-to-day tasks and operations.

• Animal cages and housing units
• Anesthesia machines
• Surgical instruments
• Microscopes
• Animal feed and water dispensers
• Animal identification systems (e.g. ear tags, microchips)
• Laboratory equipment (e.g. centrifuges, spectrophotometers)
• Animal handling and restraint equipment (e.g. gloves, masks, nets)
• Environmental control systems (e.g. temperature and humidity monitors)
• Animal waste disposal systems

Common products and services typical of NAICS Code 112990-04, illustrating the main business activities and contributions to the market.

• Laboratory mice
• Rats
• Guinea pigs
• Rabbits
• Hamsters
• Non-human primates
• Dogs
• Cats (excluding those used in research for cosmetic products)
• Fish
• Birds

The specific certifications, permits, licenses, and regulatory compliance requirements within the United States for this industry.

• Animal Welfare Act (AWA): The AWA is a federal law that regulates the treatment of animals in research, exhibition, transport, and by dealers. It is enforced by the USDA Animal and Plant Health Inspection Service (APHIS).
• Institutional Animal Care and Use Committee (IACUC) Approval: IACUC is a committee that reviews and approves animal research protocols to ensure that they comply with the AWA and other regulations. It is required by the National Institutes of Health (NIH) and other funding agencies.
• Good Laboratory Practice (GLP) Certification: GLP is a set of standards for conducting nonclinical laboratory studies that are used to support research or marketing permits for products regulated by the FDA. It is required by the FDA for safety and efficacy testing of drugs, biologics, and medical devices.
• Association for Assessment and Accreditation Of Laboratory Animal Care (AAALAC) Accreditation: AAALAC is a private, nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. It is recognized by NIH and other funding agencies as a standard for animal care and use programs.
• United States Department Of Agriculture (USDA) Animal Welfare Inspection: USDA APHIS conducts inspections of animal research facilities to ensure compliance with the AWA and other regulations. It is required by law for facilities that use animals in research, exhibition, or transport.

A concise historical narrative of NAICS Code 112990-04 covering global milestones and recent developments within the United States.

• The use of animals in laboratory research dates back to ancient Greece, where Aristotle and his followers conducted experiments on living animals. In the 19th century, the use of animals in research became more widespread, with the development of anesthesia and antiseptics. In the 20th century, the use of animals in research continued to grow, with the development of new technologies and the increasing demand for medical research. In the United States, the use of animals in research is regulated by the Animal Welfare Act, which was passed in 1966 and amended in 1970, 1976, and 1985. The act requires that research facilities provide adequate veterinary care and housing for animals used in research, and that researchers use the minimum number of animals necessary to achieve their research goals. Recent history of the industry in the United States has been marked by increased scrutiny and regulation. In 2015, the National Institutes of Health announced that it would no longer fund research on chimpanzees, except in cases where it was necessary for human health. In 2016, the U.S. Fish and Wildlife Service listed all chimpanzees as endangered, which made it more difficult to use them in research. In 2019, the U.S. Department of Agriculture announced that it would no longer regulate the treatment of birds, mice, and rats in research, which drew criticism from animal rights groups. Despite these challenges, the use of animals in research continues to be an important part of medical research in the United States.

The anticipated future trajectory of the NAICS 112990-04 industry in the USA, offering insights into potential trends, innovations, and challenges expected to shape its landscape.

• Growth Prediction: Stable

  According to a report by ResearchAndMarkets.com, the global laboratory animal models market is expected to grow at a CAGR of 8.1% from 2020 to 2027. The increasing demand for personalized medicine, rising prevalence of chronic diseases, and growing focus on R&D activities are some of the factors driving the growth of the market. In the USA, the increasing adoption of animal models in drug discovery and development is expected to drive the growth of the Animals-Laboratory Use industry. However, the increasing concerns regarding animal welfare and the availability of alternative methods are some of the factors that may hinder the growth of the industry. Overall, the industry is expected to experience steady growth in the coming years.

Recent groundbreaking advancements and milestones in the Animals-Laboratory Use industry, reflecting notable innovations that have reshaped its landscape.

• CRISPR Gene Editing Technology: This technology has revolutionized the creation of genetically modified animal models, allowing for more precise and efficient gene editing.
• 3D Printing Of Organs and Tissues: This innovation has the potential to reduce the use of live animals in research by allowing for the creation of realistic models of organs and tissues.
• Humanized Mice: These are mice that have been genetically modified to have a human immune system, allowing for more accurate testing of drugs and vaccines.
• Non-Invasive Imaging Techniques: The development of non-invasive imaging techniques such as MRI and PET scans has reduced the need for invasive procedures on animals in research.
• Organ-On-A-Chip Technology: This technology involves the creation of microfluidic devices that mimic the structure and function of human organs, allowing for more accurate testing of drugs and reducing the need for animal testing.